Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36668 | 1.00 | TSHR (0.63) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL13067061 | 1.00 | TSHR (0.63) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9058588 | 0.96 | TSHR (0.63) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL16314673 | 0.92 | TSHR (0.55) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| Bicarbonate SCHEMBL17599133 | 0.91 | TSHR (0.53) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL14422283 | 0.91 | TSHR (0.53) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL16576778 | 0.91 | TSHR (0.53) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9907091 | 0.91 | TSHR (0.53) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL12035154 | 0.90 | SMN1; SMN2 (0.55) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL17123506 | 0.89 | TSHR (0.52) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3231607-B1 | INTERLAYER COMPOSITION AND DEVICES MADE THEREFROM | XEROX CORP (US) | 2021-08-11 | — | — | EP | disclosed |