Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 7/20 | 0.51 |
| ▸ | EGFR | P00533 | 5/20 | 0.51 |
| ▸ | JAK3 | P52333 | 9/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19097594 | 0.91 | BTK (0.54) | BTKEGFRJAK3JAK1 | |
| SCHEMBL19097623 | 0.91 | BTK (0.54) | BTKEGFRJAK3JAK1 | |
| SCHEMBL23734998 | 0.87 | EGFR (0.56) | BTKEGFRJAK3 | |
| SCHEMBL19097939 | 0.87 | BTK (0.55) | BTKEGFRJAK3JAK1 | |
| SCHEMBL23735001 | 0.87 | BTK (0.55) | BTKEGFRJAK3JAK1 | |
| SCHEMBL19097831 | 0.85 | BTK (0.58) | BTKEGFRJAK3JAK1 | |
| SCHEMBL19097937 | 0.85 | BTK (0.56) | BTKEGFRJAK3JAK1 | |
| SCHEMBL23735117 | 0.84 | BTK (0.55) | BTKEGFRJAK3JAK1 | |
| SCHEMBL23735109 | 0.84 | BTK (0.52) | BTKEGFRJAK3JAK1 | |
| SCHEMBL19098101 | 0.83 | BTK (0.56) | BTKEGFRJAK3JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3398950-B1 | NOVEL KINASE INHIBITOR AGAINST WILD-TYPE EGFR AND MUTATED EGFR | PRECEDO PHARMACEUTICALS CO LTD (CN) | 2021-08-11 | — | — | EP | disclosed |