Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 5/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22206362 | 0.93 | SCN5A (0.38) | SCN5APTGS2SCN1ASCN2AAOC3 | |
| Trifluoroacetic Acid SCHEMBL22206335 | 0.85 | KMT2A (0.39) | SCN5ALMNAALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL22206330 | 0.85 | SCN5A (0.37) | SCN5APTGS2SCN1ASCN2AGPR139 | |
| Trifluoroacetic Acid SCHEMBL23736452 | 0.81 | SCN5A (0.38) | SCN5ASCN1ASCN2AAOC3 | |
| Trifluoroacetic Acid SCHEMBL22206429 | 0.80 | SCN5A (0.35) | SCN5ASCN1ASCN2AAOC3GPR139 | |
| SCHEMBL22099134 | 0.80 | SCN5A (0.40) | SCN5ASCN1ASCN2AAOC3GPR139 | |
| Trifluoroacetic Acid SCHEMBL23736450 | 0.80 | KDM4E (0.36) | SCN5ASCN1ASCN2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL22206373 | 0.79 | SCN5A (0.40) | SCN5ASCN1ASCN2AAOC3GPR139 | |
| Trifluoroacetic Acid SCHEMBL22206383 | 0.79 | CYP3A4 (0.39) | GPR139 | |
| SCHEMBL22206311 | 0.78 | SMN1; SMN2 (0.38) | SCN5ASCN1ASCN2AAOC3GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11091479-B2 | Triazolopyridin-3-ones or their salts and pharmaceutical compositions comprising the same | YUHAN CORPORATION (KR) | 2021-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091479-B2 | Triazolopyridin-3-ones or their salts and pharmaceutical compositions comprising the same | VAPB, HDLBP, VAPA | SCN5A 2529/4885PTGS2 4724/4885SCN1A 1343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.