SCHEMBL23737102

SCHEMBL23737102

c1ccc(-c2ccc(-c3nc(-c4cc(-n5c6ccccc6c6cc7ccccc7cc65)c5oc6ccccc6c5c4)nc(-c4ccc5c6ccccc6n(-c6ccccc6)c5c4)n3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TSHR P16473 2/20 0.32
ALDH1A1 P00352 4/20 0.31
PPARG P37231 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
NR2E3 Q9Y5X4 1/20 0.31
NCOR2 Q9Y618 1/20 0.31
MAPT P10636 4/20 0.31
PTGER4 P35408 1/20 0.31
LMNA P02545 2/20 0.31
CHEK2 O96017 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HPGD P15428 1/20 0.31
POLB P06746 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23738232 0.99 KDM4E (0.35) KDM4EATML3MBTL1TSHRALDH1A1
SCHEMBL23736997 0.99 KDM4E (0.35) KDM4EATML3MBTL1TSHRALDH1A1
SCHEMBL23737145 0.97 KDM4E (0.35) KDM4EATML3MBTL1TSHRALDH1A1
SCHEMBL24382499 0.96 KDM4E (0.33) KDM4EATML3MBTL1ALDH1A1PPARG
SCHEMBL23737634 0.96 KDM4E (0.35) KDM4EATML3MBTL1TSHRALDH1A1
SCHEMBL25051574 0.95 CHEK2 (0.35) KDM4EATML3MBTL1ALDH1A1PPARG
SCHEMBL25051797 0.94 KDM4E (0.34) KDM4EATML3MBTL1ALDH1A1PPARG
SCHEMBL25051746 0.94 TSHR (0.33) KDM4ETSHRALDH1A1MAPTLMNA
SCHEMBL23737026 0.94 TSHR (0.35) KDM4ETSHRALDH1A1MAPTLMNA
SCHEMBL23203695 0.94 TSHR (0.35) KDM4ETSHRALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3863077-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2022-05-04 EP disclosed
EP-3863077-A1 ORGANIC LIGHT EMITTING DIODE LG Chem, Ltd. (KR) 2021-08-11 EP disclosed