⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488329 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL1821478 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL27496594 | 0.74 | — | — | |
| Methylamine SCHEMBL27746459 | 0.72 | — | — | |
| SCHEMBL27280457 | 0.67 | — | — | |
| SCHEMBL27306956 | 0.67 | — | — | |
| Formamide SCHEMBL28311608 | 0.67 | — | — | |
| SCHEMBL27294293 | 0.67 | — | — | |
| SCHEMBL9435750 | 0.67 | — | — | |
| SCHEMBL5530412 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416933-B1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM INC (US) | 2008-01-02 | — | — | EP | claimed |
| US-20070265248-A1 | Substituted piperazines and methods of use | AMGEN INC. (US) | 2007-11-15 | — | — | US | claimed |
| US-6977264-B2 | Substituted piperidines and methods of use | AMGEN INC. (US) | 2005-12-20 | — | — | US | claimed |
| US-20040006067-A1 | Substituted piperidines and methods of use | AMGEN INC. | 2004-01-08 | — | — | US | claimed |
| US-20030220324-A1 | Substituted piperazines and methods of use | AMGEN INC. | 2003-11-27 | — | — | US | claimed |
| US-3968109-A | ANTIBIOTIC | E. R. SQUIBB & SONS, INC. (US) | 1976-07-06 | — | — | US | claimed |
| EP-2978767-B1 | DYEING METHOD USING A HAIR-DYEING PRECURSOR OBTAINED FROM IRIDOIDS, COMPOSITION, PRECURSOR AND DEVICE INCLUDING SAME | OREAL (FR) | 2018-10-03 | — | — | EP | disclosed |
| EP-2978749-A1 | OPTIONALLY PROTECTED IRIDOID-DERIVED COMPOUNDS, COMPOSITION INCLUDING SAME, USE AS A DYE FOR KERATIN FIBRES AND DEVICES | L'Oréal (FR) | 2016-02-03 | — | — | EP | disclosed |
| EP-2978767-A1 | DYEING METHOD USING A HAIR-DYEING PRECURSOR OBTAINED FROM IRIDOIDS, COMPOSITION, PRECURSOR AND DEVICE INCLUDING SAME | L'OREAL (FR) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014155016-A1 | OPTIONALLY PROTECTED IRIDOID-DERIVED COMPOUNDS, COMPOSITION INCLUDING SAME, USE AS A DYE FOR KERATIN FIBRES AND DEVICES | L'OREAL (FR) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154957-A1 | DYEING METHOD USING A HAIR-DYEING PRECURSOR OBTAINED FROM IRIDOIDS, COMPOSITION, PRECURSOR AND DEVICE INCLUDING SAME | L'OREAL (FR) | 2014-10-02 | — | — | WO | disclosed |
| WO-2011117553-A1 | DYEING METHOD USING NON-GLYCOSYLATED IRIDOID DYES, DYEING COMPOSITION AND USE THEREOF | L'OREAL (FR) | 2011-09-29 | — | — | WO | disclosed |
| WO-2011117554-A1 | DYEING METHOD USING A GLYCOSYLATED IRIDOID DERIVATIVE | L'OREAL (FR) | 2011-09-29 | — | — | WO | disclosed |
| US-6610871-B1 | Reacting with an organozinc compound; chemoselective for Sn2' substitution and/or stereoselective. | AVECIA LIMITED (GB) | 2003-08-26 | — | — | US | disclosed |
| WO-2003009847-A1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM, INC. (US) | 2003-02-06 | — | — | WO | disclosed |
| EP-1107936-A1 | COPPER-CATALYSED ENANTIOSELECTIVE ALLYLIC SUBSTITUTION REACTIONS | Avecia Limited (GB) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012449-A1 | COPPER-CATALYZED ENANTIOSELECTIVE ALLYLIC SUBSTITUTION REACTIONS | AVECIA LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |
| US-4071682-A | BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-3968109-A | ANTIBIOTIC | E. R. SQUIBB & SONS, INC. (US) | 1976-07-06 | — | — | US | disclosed |
| US-3941779-A | Method for producing 2-(substituted thio)-3-cephem derivatives | E. R. SQUIBB & SONS, INC. (US) | 1976-03-02 | — | — | US | disclosed |