SCHEMBL23738720

SCHEMBL23738720

c1ccc2c(c1)Oc1c(ccc3c1c1c4ccccc4ccc1n3-c1ccc3oc4ccccc4c3c1)C21c2ccccc2-c2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SIRT2 Q8IXJ6 1/20 0.31
SIRT1 Q96EB6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23738719 0.95 TDP1 (0.33) TDP1L3MBTL1
SCHEMBL23184385 0.90
SCHEMBL23184102 0.89 AHR (0.30)
SCHEMBL23739000 0.89
SCHEMBL23185064 0.87 SIRT2 (0.31) SIRT2SIRT1
SCHEMBL23184386 0.86
SCHEMBL23738870 0.86 KDM4E (0.33) L3MBTL1
SCHEMBL23738998 0.86 KDM4E (0.31) L3MBTL1SIRT2SIRT1
SCHEMBL23739209 0.86 SIRT2 (0.31) SIRT2SIRT1
SCHEMBL25818893 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3388438-B1 SPIRO-STRUCTURED COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2021-08-11 EP disclosed