Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23739086 | 0.97 | SIRT2 (0.32) | SIRT2SIRT1KDM4EATML3MBTL1 | |
| SCHEMBL23738883 | 0.94 | CYP1A1 (0.30) | — | |
| SCHEMBL23185107 | 0.94 | KDM4E (0.31) | KDM4EATML3MBTL1 | |
| SCHEMBL23738729 | 0.92 | — | — | |
| SCHEMBL23738907 | 0.92 | JAK2 (0.31) | — | |
| SCHEMBL23738908 | 0.92 | — | — | |
| SCHEMBL17516164 | 0.92 | SIRT2 (0.34) | SIRT2SIRT1KDM4EATML3MBTL1 | |
| SCHEMBL23739045 | 0.91 | — | — | |
| SCHEMBL23184533 | 0.91 | CYP1A1 (0.31) | — | |
| SCHEMBL23183987 | 0.91 | KDM4E (0.32) | KDM4EATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388438-B1 | SPIRO-STRUCTURED COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME | LG CHEMICAL LTD (KR) | 2021-08-11 | — | — | EP | disclosed |