Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23184237 | 0.96 | MAPT (0.33) | MAPTTSHRMAPK1NPSR1HSD17B10 | |
| SCHEMBL23738978 | 0.91 | KDM4E (0.33) | MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL23739057 | 0.89 | — | — | |
| SCHEMBL23184524 | 0.89 | KDM4E (0.30) | MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL23185009 | 0.88 | KDM4E (0.33) | MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL23184610 | 0.88 | MAPT (0.35) | MAPTTSHRMAPK1NPSR1HSD17B10 | |
| SCHEMBL20199596 | 0.88 | MAPT (0.37) | MAPTTSHRMAPK1NPSR1HSD17B10 | |
| SCHEMBL23184908 | 0.88 | KDM4E (0.33) | MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL23739016 | 0.88 | MAPT (0.33) | MAPTTSHRMAPK1NPSR1HSD17B10 | |
| SCHEMBL23184251 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388438-B1 | SPIRO-STRUCTURED COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME | LG CHEMICAL LTD (KR) | 2021-08-11 | — | — | EP | disclosed |