Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | EP300 | Q09472 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17795678 | 0.89 | EP300 (0.47) | TOP2AALDH1A1MAPTEP300KDM4E | |
| SCHEMBL19608099 | 0.86 | EP300 (0.43) | TOP2AMAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL17795679 | 0.85 | EP300 (0.50) | ALDH1A1MAPTEP300KDM4EWDR5 | |
| SCHEMBL19608100 | 0.85 | EP300 (0.49) | TOP2AMAPK1ALDH1A1MAPTEP300 | |
| SCHEMBL16392547 | 0.84 | EP300 (0.48) | TOP2AMAPK1ALDH1A1MAPTEP300 | |
| SCHEMBL17795757 | 0.84 | MAPT (0.51) | ALDH1A1MAPTLMNAEP300KDM4E | |
| SCHEMBL17795676 | 0.82 | EP300 (0.52) | ALDH1A1MAPTEP300KDM4EWDR5 | |
| SCHEMBL16392556 | 0.81 | EP300 (0.52) | ALDH1A1MAPTLMNAEP300KDM4E | |
| SCHEMBL19608160 | 0.80 | EP300 (0.50) | TOP2AMAPTEP300CA12CA1 | |
| SCHEMBL17795756 | 0.80 | MAPT (0.52) | ALDH1A1MAPTLMNAEP300KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3224238-B1 | NOVEL CYSTOBACTAMIDES | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2021-08-11 | — | — | EP | disclosed |