Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL2373983

C=C(C)C.N.O=C1CCC(=O)O1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21259 0.97 TSHR (0.65) TSHRALDH1A1LMNATP53
SCHEMBL9724356 0.97 TSHR (0.65) TSHRALDH1A1LMNATP53
SCHEMBL11269485 0.97 TSHR (0.65) TSHRALDH1A1LMNATP53
SCHEMBL28743003 0.94 TSHR (0.61) TSHRALDH1A1LMNATP53
SCHEMBL27368492 0.94 TSHR (0.61) TSHRALDH1A1LMNATP53
SCHEMBL28533853 0.94 TSHR (0.61) TSHRALDH1A1LMNATP53
Ethylene SCHEMBL29140016 0.94 TSHR (0.61) TSHRALDH1A1LMNATP53
Hydroxyamine SCHEMBL27346314 0.92 TSHR (0.58) TSHRALDH1A1LMNATP53
SCHEMBL28539245 0.89 TSHR (0.61) TSHRALDH1A1LMNATP53
Ethylene Glycol SCHEMBL29140022 0.87 TSHR (0.52) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023086886-A2 SUSTAINABLE LUBRICANTS EVOLVE LUBRICANTS, INC. (US) 2023-05-19 WO disclosed
US-9228147-B2 Glycol ether-based cyclohexanoate esters, their synthesis and methods of use EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-01-05 US disclosed
EP-2366763-B1 Ashless detergents and formulated lubricating oil containing same EXXONMOBIL RES & ENG CO (US) 2014-07-02 EP disclosed
EP-2450422-B1 Premium wear-resistant lubricant containing non-ionic ashless anti-wear additives EXXONMOBIL RES & ENG CO (US) 2013-10-30 EP disclosed
EP-1899444-B1 ASHLESS DETERGENTS AND FORMULATED LUBRICATING OIL CONTAINING SAME EXXONMOBIL RES & ENG CO (US) 2013-08-28 EP disclosed
EP-1833950-B1 PREMIUM WEAR-RESISTANT LUBRICANT CONTAINING NON-IONIC ASHLESS ANTI-WEAR ADDITIVES EXXONMOBIL RES & ENG CO (US) 2012-10-17 EP disclosed
WO-2012082826-A1 GLYCOL ETHER-BASED CYCLOHEXANOATE ESTERS, THEIR SYNTHESIS AND METHODS OF USE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-06-21 WO disclosed
US-20120149620-A1 GLYCOL ETHER-BASED CYCLOHEXANOATE ESTERS, THEIR SYNTHESIS AND METHODS OF USE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-06-14 US disclosed
EP-2450422-A1 Premium wear-resistant lubricant containing non-ionic ashless anti-wear additives ExxonMobil Research and Engineering Company (US) 2012-05-09 EP disclosed
EP-2366763-A1 Ashless detergents and formulated lubricating oil containing same ExxonMobil Research and Engineering Company (US) 2011-09-21 EP disclosed
EP-1144551-A2 WIDE-CUT SYNTHETIC ISOPARAFFINIC LUBRICATING OILS ExxonMobil Research and Engineering Company (US) 2001-10-17 EP disclosed
EP-1114132-A2 PREMIUM WEAR RESISTANT LUBRICANT ExxonMobil Research and Engineering Company (US) 2001-07-11 EP disclosed
EP-1114131-A2 PREMIUM SYNTHETIC LUBRICANTS ExxonMobil Research and Engineering Company (US) 2001-07-11 EP disclosed
EP-1114127-A1 PRODUCTION ON SYNTHETIC LUBRICANT AND LUBRICANT BASE STOCK WITHOUT DEWAXING ExxonMobil Research and Engineering Company (US) 2001-07-11 EP disclosed
US-6165949-A Premium wear resistant lubricant EXXON RESEARCH AND ENGINEERING COMPANY (US) 2000-12-26 US disclosed
US-6103099-A HYDROISOMERIZATION WAXY PARAFFINIC LUBRICANTS BY FISCHER TROPSCH SYNTHESIZED HYDROCARBON FEEDS WITH GROUPVIII NONNOBLE CATALYST WITH ACID CARRIERS EXXON RESEARCH AND ENGINEERING COMPANY (US) 2000-08-15 US disclosed
WO-2000015736-A2 WIDE-CUT SYNTHETIC ISOPARAFFINIC LUBRICATING OILS EXXON RESEARCH AND ENGINEERING COMPANY (US) 2000-03-23 WO disclosed
WO-2000014187-A2 PREMIUM SYNTHETIC LUBRICANTS EXXON RESEARCH AND ENGINEERING COMPANY (US) 2000-03-16 WO disclosed
WO-2000014188-A2 PREMIUM WEAR RESISTANT LUBRICANT EXXON RESEARCH AND ENGINEERING COMPANY (US) 2000-03-16 WO disclosed
WO-2000014183-A1 PRODUCTION ON SYNTHETIC LUBRICANT AND LUBRICANT BASE STOCK WITHOUT DEWAXING EXXON RESEARCH AND ENGINEERING COMPANY (US) 2000-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149620-A1 GLYCOL ETHER-BASED CYCLOHEXANOATE ESTERS, THEIR SYNTHESIS AND METHODS OF USE GNE, UGT8, GK TSHR 3796/4885ALDH1A1 2138/4885LMNA 1938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.