Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.78 |
| ▸ | DYRK1A | Q13627 | 19/20 | 0.78 |
| ▸ | WNT1 | P04628 | 11/20 | 0.78 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20938563 | 0.89 | GSK3B (0.74) | GSK3BDYRK1AWNT1ABL1 | |
| SCHEMBL19516218 | 0.88 | DYRK1A (1.00) | GSK3BDYRK1AWNT1ABL1 | |
| SCHEMBL30005459 | 0.88 | DYRK1A (1.00) | GSK3BDYRK1AWNT1ABL1 | |
| SCHEMBL19515593 | 0.85 | GSK3B (1.00) | GSK3BDYRK1AWNT1 | |
| SCHEMBL30004491 | 0.85 | GSK3B (1.00) | GSK3BDYRK1AWNT1 | |
| SCHEMBL19516069 | 0.83 | GSK3B (0.84) | GSK3BDYRK1AWNT1 | |
| SCHEMBL30004871 | 0.83 | GSK3B (0.84) | GSK3BDYRK1AWNT1 | |
| SCHEMBL19515734 | 0.80 | GSK3B (0.90) | GSK3BDYRK1AWNT1 | |
| SCHEMBL20938934 | 0.79 | GSK3B (0.72) | GSK3BDYRK1AWNT1ABL1 | |
| SCHEMBL19515768 | 0.79 | DYRK1A (0.90) | GSK3BDYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3448838-B1 | ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF | BIOSPLICE THERAPEUTICS INC (US) | 2021-08-11 | — | — | EP | disclosed |