Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 19/20 | 0.62 |
| ▸ | WNT1 | P04628 | 14/20 | 0.62 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23741354 | 0.85 | GSK3B (0.59) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23740979 | 0.83 | GSK3B (0.58) | GSK3BDYRK1AWNT1MLLT1 | |
| SCHEMBL20938487 | 0.81 | GSK3B (0.62) | GSK3BDYRK1AWNT1 | |
| SCHEMBL24219438 | 0.80 | GSK3B (0.59) | GSK3BDYRK1AWNT1 | |
| SCHEMBL24219625 | 0.80 | GSK3B (0.65) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23741122 | 0.79 | DYRK1A (0.62) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23741171 | 0.79 | GSK3B (0.60) | GSK3BDYRK1AWNT1MLLT1 | |
| SCHEMBL19515359 | 0.76 | GSK3B (1.00) | GSK3BDYRK1AWNT1 | |
| SCHEMBL19516070 | 0.76 | GSK3B (1.00) | GSK3BDYRK1AWNT1 | |
| SCHEMBL19515362 | 0.76 | GSK3B (1.00) | GSK3BDYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3448838-B1 | ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF | BIOSPLICE THERAPEUTICS INC (US) | 2021-08-11 | — | — | EP | disclosed |