Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 20/20 | 0.57 |
| ▸ | WNT1 | P04628 | 19/20 | 0.57 |
| ▸ | CLK2 | P49760 | 3/20 | 0.48 |
| ▸ | CLK3 | P49761 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19516467 | 0.89 | GSK3B (0.69) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL30004474 | 0.89 | GSK3B (0.69) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL28895344 | 0.76 | GSK3B (0.69) | GSK3BDYRK1AWNT1 | |
| SCHEMBL28895289 | 0.74 | GSK3B (0.59) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19516069 | 0.73 | GSK3B (0.84) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL30004871 | 0.73 | GSK3B (0.84) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19515838 | 0.73 | GSK3B (1.00) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL24219332 | 0.73 | GSK3B (0.77) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL30005689 | 0.73 | GSK3B (1.00) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL23741054 | 0.72 | GSK3B (0.62) | GSK3BDYRK1AWNT1CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3448838-B1 | ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF | BIOSPLICE THERAPEUTICS INC (US) | 2021-08-11 | — | — | EP | disclosed |