Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CD209 | Q9NNX6 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23742913 | 0.93 | SLC5A2 (0.43) | SLC5A2MCL1PPARGPPARAALDH1A1 | |
| SCHEMBL23742933 | 0.93 | SLC5A2 (0.43) | SLC5A2MCL1PPARGPPARAALDH1A1 | |
| SCHEMBL23743007 | 0.92 | SLC2A1 (0.47) | SLC5A2MCL1PPARGPPARAALDH1A1 | |
| SCHEMBL23743010 | 0.92 | SLC2A1 (0.47) | SLC5A2MCL1PPARGPPARAALDH1A1 | |
| SCHEMBL23742998 | 0.92 | SLC2A1 (0.47) | SLC5A2MCL1PPARGPPARAALDH1A1 | |
| SCHEMBL23743008 | 0.92 | SLC2A1 (0.47) | SLC5A2MCL1PPARGPPARAALDH1A1 | |
| SCHEMBL23742872 | 0.92 | SLC2A1 (0.47) | SLC5A2MCL1PPARGPPARAALDH1A1 | |
| SCHEMBL23742968 | 0.84 | CD209 (0.50) | SLC5A2CD209 | |
| SCHEMBL23742974 | 0.83 | PPARG (0.41) | SLC5A2MCL1PPARGPPARAALDH1A1 | |
| SCHEMBL23742908 | 0.83 | SLC2A1 (0.47) | SLC5A2SLC2A1CD209HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155748-A1 | INHIBITORS OF MALARIAL AND PLASMODIUM FALCIPARUM HEXOSE TRANSPORTER AND USES THEREOF | TSINGHUA UNIVERSITY (CN) | 2021-08-12 | — | — | WO | disclosed |