Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.51 |
| ▸ | CDC25B | P30305 | 8/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | GJB2 | P29033 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.47 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.47 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154719 | 1.00 | NT5E (0.51) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL27652412 | 1.00 | NT5E (0.51) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL7155265 | 1.00 | NT5E (0.51) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL25585675 | 1.00 | NT5E (0.51) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL7156143 | 1.00 | NT5E (0.51) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL7639364 | 1.00 | NT5E (0.51) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL7753913 | 0.93 | SLC6A2 (0.52) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL10865849 | 0.92 | SLC6A2 (0.53) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL24479039 | 0.92 | SLC6A2 (0.53) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL4587088 | 0.91 | SSTR5 (0.58) | NT5EPTPN1CDC25BPTPN2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155748-A1 | INHIBITORS OF MALARIAL AND PLASMODIUM FALCIPARUM HEXOSE TRANSPORTER AND USES THEREOF | TSINGHUA UNIVERSITY (CN) | 2021-08-12 | — | — | WO | disclosed |