⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27350163 | 0.98 | EPHX1 (0.37) | — | |
| SCHEMBL17675657 | 0.95 | EPHX1 (0.38) | — | |
| SCHEMBL20032245 | 0.93 | EPHX1 (0.37) | — | |
| SCHEMBL20031997 | 0.93 | EPHX1 (0.37) | — | |
| SCHEMBL20031998 | 0.93 | EPHX1 (0.37) | — | |
| SCHEMBL5683395 | 0.93 | EPHX1 (0.37) | — | |
| SCHEMBL12984443 | 0.90 | — | — | |
| SCHEMBL23697388 | 0.90 | EPHX1 (0.34) | — | |
| SCHEMBL19179014 | 0.82 | EPHX1 (0.33) | — | |
| SCHEMBL14704905 | 0.82 | HCAR2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240245670-A1 | DOSING REGIMEN AND PHARMACEUTICAL COMBINATION COMPRISING 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES | NOVARTIS AG (CH) | 2024-07-25 | — | — | US | disclosed |
| US-20230321067-A1 | DOSING REGIMEN COMPRISING 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. | 2023-10-12 | — | — | US | disclosed |
| WO-2021158412-A1 | ELECTROCHEMICALLY-CLEAVABLE LINKERS | MICROSOFT TECHNOLOGY LICENSING, LLC (US) | 2021-08-12 | — | — | WO | disclosed |