Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 11/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30345587 | 0.87 | CHRM4 (0.49) | CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL26086906 | 0.87 | CHRM4 (0.49) | CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL23744074 | 0.87 | CHRM4 (0.76) | CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL23744037 | 0.84 | CHRM2 (0.59) | CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL23744118 | 0.84 | CHRM2 (0.59) | CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL23744442 | 0.83 | CHRM2 (0.76) | CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL23744544 | 0.82 | HCAR2 (0.57) | CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL23744728 | 0.82 | HCAR2 (0.57) | CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL26430622 | 0.82 | CHRM4 (0.71) | CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL23744242 | 0.81 | CHRM4 (0.75) | CHRM4CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158698-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |