Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.76 |
| ▸ | CHRM4 | P08173 | 15/20 | 0.67 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.65 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23744301 | 1.00 | CHRM2 (0.76) | CHRM2CHRM4CHRM3CHRM5CHRM1 | |
| SCHEMBL23744284 | 0.92 | CHRM4 (0.68) | CHRM2CHRM4CHRM3CHRM5CHRM1 | |
| SCHEMBL23744283 | 0.92 | CHRM4 (0.68) | CHRM2CHRM4CHRM3CHRM5CHRM1 | |
| SCHEMBL23744642 | 0.91 | CHRM4 (0.75) | CHRM2CHRM4CHRM3CHRM5CHRM1 | |
| SCHEMBL23744242 | 0.91 | CHRM4 (0.75) | CHRM2CHRM4CHRM3CHRM5CHRM1 | |
| SCHEMBL23744243 | 0.91 | CHRM4 (0.75) | CHRM2CHRM4CHRM3CHRM5CHRM1 | |
| SCHEMBL23744162 | 0.90 | CHRM4 (0.64) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL23744300 | 0.90 | CHRM4 (0.65) | CHRM2CHRM4CHRM3CHRM5CHRM1 | |
| SCHEMBL23744335 | 0.87 | CHRM4 (0.67) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL26087096 | 0.87 | CHRM2 (0.64) | CHRM2CHRM4CHRM3CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230129359-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. | 2023-04-27 | — | — | US | disclosed |
| WO-2021158698-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230129359-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | CHRM4, CHRM2, CHRM5 | CHRM2 2/4885CHRM4 1/4885CHRM3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.