Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 10/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.65 |
| ▸ | CHRM4 | P08173 | 10/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23744333 | 1.00 | CHRM2 (0.65) | CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL23744230 | 0.95 | CHRM2 (0.67) | CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL23744295 | 0.93 | CHRM2 (0.65) | CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL23744233 | 0.93 | CHRM2 (0.65) | CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL23744285 | 0.93 | CHRM2 (0.65) | CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL23744294 | 0.93 | CHRM2 (0.65) | CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL23744585 | 0.92 | CHRM2 (0.77) | CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL23744640 | 0.92 | CHRM2 (0.77) | CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL23744289 | 0.91 | CHRM2 (0.65) | CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL23744239 | 0.91 | CHRM2 (0.60) | CHRM2CHRM1CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158698-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |