Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.75 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.75 |
| ▸ | CHRM4 | P08173 | 12/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.61 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23744495 | 0.95 | CHRM3 (0.69) | CHRM3CHRM5CHRM1CHRM4CHRM2 | |
| SCHEMBL26430563 | 0.95 | CHRM3 (0.70) | CHRM3CHRM5CHRM1CHRM4CHRM2 | |
| SCHEMBL23744243 | 0.90 | CHRM4 (0.75) | CHRM3CHRM5CHRM1CHRM4CHRM2 | |
| SCHEMBL23744642 | 0.90 | CHRM4 (0.75) | CHRM3CHRM5CHRM1CHRM4CHRM2 | |
| SCHEMBL23744242 | 0.90 | CHRM4 (0.75) | CHRM3CHRM5CHRM1CHRM4CHRM2 | |
| SCHEMBL26429256 | 0.88 | CHRM3 (0.63) | CHRM3CHRM5CHRM1CHRM4CHRM2 | |
| SCHEMBL29432098 | 0.86 | CHRM3 (1.00) | CHRM3CHRM5CHRM1CHRM4CHRM2 | |
| SCHEMBL26430653 | 0.85 | CHRM4 (0.71) | CHRM3CHRM5CHRM1CHRM4CHRM2 | |
| SCHEMBL23744497 | 0.84 | CHRM5 (0.56) | CHRM3CHRM5CHRM1CHRM4CHRM2 | |
| SCHEMBL23744439 | 0.84 | CHRM5 (0.56) | CHRM3CHRM5CHRM1CHRM4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158698-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |