Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 10/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23744500 | 1.00 | CHRM4 (0.59) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL23744502 | 1.00 | CHRM4 (0.59) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL23744110 | 1.00 | CHRM4 (0.59) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL23744282 | 0.92 | CHRM4 (0.51) | CHRM4CHRM2CHRM3PRKAA2 | |
| SCHEMBL23744160 | 0.91 | CHRM2 (0.58) | CHRM4CHRM2CHRM3PRKAA2 | |
| SCHEMBL23744244 | 0.88 | CHRM4 (0.76) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL23744499 | 0.88 | CHRM4 (0.76) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL23744106 | 0.88 | CHRM4 (0.61) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL23744107 | 0.88 | CHRM4 (0.61) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL26090313 | 0.87 | CHRM4 (0.49) | CHRM4CHRM2CHRM1CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158698-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |