Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 8/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 11/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26431987 | 0.93 | CHRM4 (0.55) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL23744646 | 0.90 | CHRM2 (0.57) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL23744476 | 0.90 | CHRM2 (0.57) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL30345435 | 0.88 | CHRM4 (0.49) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL26429439 | 0.88 | CHRM4 (0.49) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL23744269 | 0.87 | CHRM2 (0.54) | CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL23744046 | 0.84 | CHRM4 (0.62) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL23744043 | 0.84 | CHRM4 (0.62) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL23744225 | 0.84 | CHRM2 (0.56) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL23744226 | 0.84 | CHRM2 (0.56) | CHRM4CHRM2CHRM1CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158698-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |