Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 11/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23744649 | 1.00 | CHRM2 (0.45) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL26432039 | 0.94 | CHRM2 (0.42) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL26432005 | 0.94 | CHRM2 (0.42) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL26429441 | 0.88 | CHRM2 (0.37) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL26429445 | 0.88 | CHRM2 (0.37) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL23744476 | 0.87 | CHRM2 (0.57) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL23744646 | 0.87 | CHRM2 (0.57) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL23744618 | 0.86 | CHRM4 (0.47) | CHRM2CHRM1CHRM4CHRM3BCHE | |
| SCHEMBL23744614 | 0.86 | CHRM4 (0.47) | CHRM2CHRM1CHRM4CHRM3BCHE | |
| SCHEMBL23744482 | 0.85 | CHRM2 (0.53) | CHRM2CHRM1CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158698-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |