SCHEMBL2374488

SCHEMBL2374488

CCCCCCCCCCCCC/C(=C/C(=O)[O-])C(=O)[O-].CCCCCCCCCCCCC/C(=C/C(=O)[O-])C(=O)[O-].CCCC[Sn+2]CCCC.CCCC[Sn+2]CCCC.O=C([O-])/C=C(/Cc1ccccc1)C(=O)[O-].O=C([O-])/C=C(/Cc1ccccc1)C(=O)[O-]

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
EPHX2 P34913 4/20 0.40
CES2 O00748 2/20 0.40
CES1 P23141 2/20 0.40
FAAH O00519 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CNR2 P34972 2/20 0.37
CNR1 P21554 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
SOAT2 O75908 1/20 0.35
SOAT1 P35610 1/20 0.35
CETP P11597 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6222318 0.93 CNR2 (0.39) MEN1KMT2AEPHX2CES2CES1
SCHEMBL6222330 0.93 CNR2 (0.39) MEN1KMT2AEPHX2CES2CES1
SCHEMBL2374494 0.92 MEN1 (0.41) MEN1KMT2AEPHX2CES2CES1
SCHEMBL2293072 0.85 FABP3 (0.44) MEN1KMT2ACES2CES1ALDH1A1
SCHEMBL2293061 0.85 FABP3 (0.44) MEN1KMT2ACES2CES1ALDH1A1
SCHEMBL916238 0.81 MEN1 (0.43) MEN1KMT2AEPHX2CES2CES1
SCHEMBL7052060 0.81 EPHX2 (0.44) MEN1KMT2AEPHX2CES2CES1
SCHEMBL1992846 0.81 EPHX2 (0.44) MEN1KMT2AEPHX2CES2CES1
SCHEMBL30363228 0.81 MEN1 (0.43) MEN1KMT2AEPHX2CES2CES1
SCHEMBL916235 0.81 MEN1 (0.43) MEN1KMT2AEPHX2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1734079-B1 SINGLE-COMPONENT CURABLE COMPOSITION KANEKA CORP (JP) 2016-01-20 EP disclosed
EP-2366733-B1 Curable composition improved in curability and storage stability KANEKA CORP (JP) 2014-10-22 EP disclosed
EP-1930375-B1 CURABLE COMPOSITION IMPROVED IN CURABILITY AND ADHESIVENESS KANEKA CORP (JP) 2012-07-04 EP disclosed
EP-2366733-A2 Curable composition improved in curability and storage stability KANEKA CORPORATION (JP) 2011-09-21 EP disclosed
EP-1942153-B1 CURABLE COMPOSITION IMPROVED IN CURABILITY AND STORAGE STABILITY KANEKA CORP (JP) 2010-11-17 EP disclosed
US-20090281253-A1 CURABLE COMPOSITION IMPROVED IN CURABILITY AND STORAGE STABILITY KANEKA CORPORATION (JP) 2009-11-12 US disclosed
US-20080269405-A1 Single-Component Curable Composition KANEKA CORPORATION (JP) 2008-10-30 US disclosed
EP-1942153-A1 CURABLE COMPOSITION IMPROVED IN CURABILITY AND STORAGE STABILITY Kaneka Corporation (JP) 2008-07-09 EP disclosed
EP-1930375-A1 CURABLE COMPOSITION IMPROVED IN CURABILITY AND ADHESIVENESS Kaneka Corporation (JP) 2008-06-11 EP disclosed
US-20080021140-A1 Curable Composition KANEKA CORPORATION (JP) 2008-01-24 US disclosed
US-20070203297-A1 Curable Composition KANEKA CORPORATION 2007-08-30 US disclosed
EP-1736511-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2006-12-27 EP disclosed
EP-1734079-A1 SINGLE-COMPONENT CURABLE COMPOSITION Kaneka Corporation (JP) 2006-12-20 EP disclosed
EP-1731574-A1 SINGLE-COMPONENT CURABLE COMPOSITION KANEKA CORPORATION (JP) 2006-12-13 EP disclosed
EP-1731573-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2006-12-13 EP disclosed