⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22652946 | 1.00 | — | — | |
| SCHEMBL516829 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL21200542 | 0.98 | SLC6A2 (0.31) | — | |
| SCHEMBL2373072 | 0.91 | SLC6A2 (0.31) | — | |
| SCHEMBL7852934 | 0.91 | SSTR4 (0.32) | — | |
| SCHEMBL7856435 | 0.91 | SSTR4 (0.35) | — | |
| SCHEMBL27893513 | 0.89 | — | — | |
| SCHEMBL27684537 | 0.89 | — | — | |
| SCHEMBL7853582 | 0.89 | SSTR4 (0.37) | — | |
| Hydrochloric Acid SCHEMBL28974480 | 0.89 | SLC6A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667634-B2 | Inhibitors of RAF kinases | KINNATE BIOPHARMA INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-11667634-B2 | Inhibitors of RAF kinases | KINNATE BIOPHARMA INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-20210246135-A1 | INHIBITORS OF RAF KINASES | Pierre Fabre Médicament (FR) | 2021-08-12 | — | — | US | disclosed |