Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.83 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.83 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.83 |
| ▸ | NCOR1 | O75376 | 2/20 | 0.83 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.83 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.83 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23746023 | 0.91 | HDAC1 (1.00) | HDAC1HDAC3HDAC2NCOR1HDAC8 | |
| SCHEMBL23745967 | 0.89 | HDAC1 (0.83) | HDAC1HDAC3HDAC2NCOR1HDAC8 | |
| SCHEMBL23745971 | 0.88 | HDAC1 (0.78) | HDAC1HDAC3HDAC2NCOR1HDAC8 | |
| SCHEMBL23745964 | 0.86 | HDAC1 (0.78) | HDAC1HDAC3HDAC2NCOR1HDAC8 | |
| SCHEMBL23745965 | 0.83 | HDAC1 (0.78) | HDAC1HDAC3HDAC2NCOR1HDAC8 | |
| SCHEMBL23746010 | 0.83 | HDAC1 (0.77) | HDAC1HDAC3HDAC2NCOR1HDAC8 | |
| SCHEMBL23746011 | 0.79 | HDAC1 (0.71) | HDAC1HDAC3HDAC2NCOR1HDAC8 | |
| SCHEMBL23746009 | 0.78 | HDAC1 (0.69) | HDAC1HDAC3HDAC2NCOR1HDAC8 | |
| SCHEMBL27114491 | 0.78 | HDAC1 (0.63) | HDAC1HDAC3HDAC2NCOR1HDAC8 | |
| SCHEMBL23746025 | 0.78 | HDAC1 (0.76) | HDAC1HDAC3HDAC2NCOR1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158869-A1 | COMPOUNDS, COMPOSITIONS, METHODS FOR TREATING DISEASES AND NERVE DAMAGE, AND METHODS FOR PREPARING COMPOUNDS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2021-08-12 | — | — | WO | disclosed |