Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TACR3 | P29371 | 1/20 | 0.49 |
| ▸ | ACACA | Q13085 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23722853 | 0.86 | ACACB (0.66) | ACACBMEN1CACNA1BAPBA1KMT2A | |
| SCHEMBL23722823 | 0.82 | GAA (0.58) | ACACBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL23722822 | 0.81 | KDM4E (0.69) | MEN1CACNA1BAPBA1KMT2AALDH1A1 | |
| SCHEMBL23722914 | 0.81 | KDM4E (0.67) | MEN1KMT2AALDH1A1KDM4ETACR3 | |
| SCHEMBL23746703 | 0.80 | CACNA1B (0.62) | MEN1CACNA1BAPBA1KMT2AALDH1A1 | |
| SCHEMBL23746673 | 0.79 | MEN1 (0.60) | MEN1CACNA1BAPBA1KMT2AALDH1A1 | |
| SCHEMBL23746698 | 0.78 | KDM4E (0.63) | ACACBALDH1A1KDM4EL3MBTL1TACR3 | |
| SCHEMBL23746385 | 0.77 | MOK (0.65) | MEN1CACNA1BAPBA1KMT2AALDH1A1 | |
| SCHEMBL4391974 | 0.76 | ACACB (0.74) | ACACBALDH1A1KDM4EL3MBTL1TACR3 | |
| SCHEMBL4391971 | 0.76 | ACACB (0.74) | ACACBALDH1A1KDM4EL3MBTL1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210244721-A1 | SMALL MOLECULE ENTEROVIRUS INHIBITORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210244721-A1 | SMALL MOLECULE ENTEROVIRUS INHIBITORS AND USES THEREOF | AR, KLK3, BRDT | ACACB 3935/4885MEN1 56/4885CACNA1B 1847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.