Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747784 | 0.80 | SMN1; SMN2 (0.58) | MEN1KMT2AL3MBTL1SMN1; SMN2HDAC1 | |
| SCHEMBL17916794 | 0.72 | SMN1; SMN2 (0.88) | MEN1KMT2AL3MBTL1SMN1; SMN2HDAC1 | |
| SCHEMBL23747428 | 0.71 | SMN1; SMN2 (0.75) | MEN1KMT2AL3MBTL1SMN1; SMN2HDAC1 | |
| SCHEMBL23747385 | 0.70 | SMN1; SMN2 (0.70) | MEN1KMT2AL3MBTL1SMN1; SMN2HDAC1 | |
| SCHEMBL23728131 | 0.70 | SMN1; SMN2 (0.73) | MEN1KMT2AL3MBTL1SMN1; SMN2HDAC1 | |
| Hydrochloric Acid SCHEMBL26100519 | 0.69 | SMN1; SMN2 (0.68) | MEN1KMT2AL3MBTL1SMN1; SMN2HDAC1 | |
| Hydrochloric Acid SCHEMBL23728254 | 0.69 | SMN1; SMN2 (0.68) | MEN1KMT2AL3MBTL1SMN1; SMN2HDAC1 | |
| SCHEMBL23747822 | 0.68 | SMN1; SMN2 (0.75) | MEN1KMT2AL3MBTL1SMN1; SMN2HDAC1 | |
| SCHEMBL23727608 | 0.68 | MEN1 (0.81) | MEN1KMT2AL3MBTL1SMN1; SMN2HDAC1 | |
| SCHEMBL23747521 | 0.68 | SMN1; SMN2 (0.67) | MEN1KMT2AL3MBTL1SMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021159015-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |