Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23728178 | 0.85 | JAK3 (0.79) | JAK3 | |
| SCHEMBL23728179 | 0.85 | JAK3 (0.79) | JAK3 | |
| SCHEMBL6919623 | 0.85 | JAK3 (1.00) | JAK3 | |
| Hydrochloric Acid SCHEMBL1993126 | 0.84 | JAK3 (0.98) | JAK3 | |
| SCHEMBL26099534 | 0.81 | SMN1; SMN2 (0.61) | JAK3SMN1; SMN2NPC1RAB9AHDAC1 | |
| SCHEMBL23727836 | 0.81 | SMN1; SMN2 (0.56) | JAK3SMN1; SMN2NPC1RAB9AHDAC1 | |
| SCHEMBL26100197 | 0.81 | SMN1; SMN2 (0.56) | JAK3SMN1; SMN2NPC1RAB9AHDAC1 | |
| SCHEMBL26100564 | 0.81 | SMN1; SMN2 (0.56) | JAK3SMN1; SMN2NPC1RAB9AHDAC1 | |
| SCHEMBL23727833 | 0.81 | SMN1; SMN2 (0.56) | JAK3SMN1; SMN2NPC1RAB9AHDAC1 | |
| SCHEMBL23747466 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021159015-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |