Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | GPR39 | O43194 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29715028 | 1.00 | PI4KB (0.55) | PI4KBKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL23747999 | 0.90 | PI4KB (0.49) | PI4KBKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL29715030 | 0.90 | PI4KB (0.49) | PI4KBKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL29715021 | 0.78 | PI4KB (0.62) | PI4KBKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL23024624 | 0.78 | PI4KB (0.62) | PI4KBKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL31087417 | 0.78 | PI4KB (0.47) | PI4KBKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL20533900 | 0.76 | PI4KB (0.51) | PI4KBKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL23747995 | 0.72 | KDM4E (0.46) | PI4KBKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL23012135 | 0.71 | CYP1A2 (0.37) | PI4KBKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL23012288 | 0.70 | PI4KB (0.53) | PI4KBKDM4EALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3864017-A1 | 2,6-DIMETHYL-N-((PYRIDIN-4-YL)METHYL)IMIDAZO[1,2-B]PYRIDAZIN-8-AMINE AND 2,5-DIMETHYL-N-[(PYRIDIN-4-YL)METHYL]PYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE DERIVATIVES FOR TREATING VIRAL INFECTIONS | CUROVIR AB (SE) | 2021-08-18 | — | — | EP | disclosed |