⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Homoserine SCHEMBL6446994 | 0.97 | GSR (0.59) | — | |
| Homoserine SCHEMBL29649 | 0.97 | — | — | |
| Homoserine SCHEMBL60060 | 0.97 | — | — | |
| Homoserine SCHEMBL6447119 | 0.97 | GSR (0.59) | — | |
| Homoserine SCHEMBL4944178 | 0.97 | GSR (0.59) | — | |
| Homoserine SCHEMBL29648 | 0.97 | — | — | |
| Homoserine SCHEMBL17913373 | 0.94 | — | — | |
| Homoserine SCHEMBL27622436 | 0.94 | — | — | |
| Homoserine SCHEMBL9471942 | 0.94 | GSR (0.56) | — | |
| Homoserine SCHEMBL9471940 | 0.94 | GSR (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11952583-B2 | Downy mildew resistant lettuce mutant | NUNHEMS B.V. (NL) | 2024-04-09 | — | — | US | disclosed |
| US-20210348187-A1 | DOWNY MILDEW RESISTANT LETTUCE MUTANT | NUNHEMS B.V. (NL) | 2021-11-11 | — | — | US | disclosed |
| EP-3864145-A1 | DOWNY MILDEW RESISTANT LETTUCE MUTANT | Nunhems B.V. (NL) | 2021-08-18 | — | — | EP | disclosed |