Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.48 |
| ▸ | CA1 | P00915 | 11/20 | 0.48 |
| ▸ | CA9 | Q16790 | 9/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | CA3 | P07451 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4910425 | 0.83 | TP53 (0.45) | CA2CA1CA9TP53FAAH | |
| SCHEMBL16143482 | 0.83 | TP53 (0.45) | CA2CA1CA9TP53FAAH | |
| SCHEMBL11867687 | 0.83 | TP53 (0.45) | CA2CA1CA9TP53FAAH | |
| SCHEMBL18063451 | 0.83 | CA1 (0.50) | CA2CA1CA9CA12CA7 | |
| SCHEMBL14836535 | 0.82 | TP53 (0.44) | CA2TP53FAAHOPRM1CNR1 | |
| SCHEMBL14837354 | 0.82 | TP53 (0.44) | CA2TP53FAAHOPRM1CNR1 | |
| SCHEMBL8843279 | 0.82 | TP53 (0.44) | CA2TP53FAAHOPRM1CNR1 | |
| SCHEMBL14185392 | 0.82 | TP53 (0.44) | CA2TP53FAAHOPRM1CNR1 | |
| SCHEMBL22263512 | 0.82 | TP53 (0.44) | CA2TP53FAAHOPRM1CNR1 | |
| SCHEMBL8843220 | 0.82 | TP53 (0.44) | CA2TP53FAAHOPRM1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3864003-A1 | PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2021-08-18 | — | — | EP | disclosed |