Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26449223 | 1.00 | HDAC6 (0.32) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL26449279 | 1.00 | HDAC6 (0.32) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL59435 | 0.87 | CA1 (0.33) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL2160514 | 0.87 | CA1 (0.33) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL67120 | 0.87 | CA1 (0.33) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL1486172 | 0.86 | AAK1 (0.32) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL6843570 | 0.86 | AAK1 (0.32) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL28520254 | 0.86 | AAK1 (0.32) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL1486174 | 0.86 | AAK1 (0.32) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL28058555 | 0.86 | CA1 (0.32) | HDAC6HDAC1HDAC2MMP13AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158899-A1 | ELONGATION FACTOR 1-ALPHA INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-12 | — | — | WO | disclosed |