SCHEMBL23749967

SCHEMBL23749967

CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CCC(=O)NCCCCNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 20/20 0.63
▸ MC3R P41968 15/20 0.58
▸ MC5R P33032 7/20 0.58
▸ MC1R Q01726 7/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24991492 1.00 MC4R (0.63) MC4RMC3RMC5RMC1R
SCHEMBL23750212 1.00 MC4R (0.63) MC4RMC3RMC5RMC1R
SCHEMBL24991010 1.00 MC4R (0.63) MC4RMC3RMC5RMC1R
SCHEMBL23750221 1.00 MC4R (0.63) MC4RMC3RMC5RMC1R
SCHEMBL24991170 0.98 MC4R (0.61) MC4RMC3RMC5RMC1R
SCHEMBL23750193 0.98 MC4R (0.61) MC4RMC3RMC5RMC1R
SCHEMBL24990148 0.98 MC4R (0.61) MC4RMC3RMC5RMC1R
SCHEMBL23750194 0.98 MC4R (0.61) MC4RMC3RMC5RMC1R
SCHEMBL24989721 0.98 MC4R (0.60) MC4RMC3RMC5RMC1R
SCHEMBL23750220 0.98 MC4R (0.60) MC4RMC3RMC5RMC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications PALATIN TECHNOLOGIES, INC. (US) 2023-02-09 — — US disclosed
WO-2021158463-A1 DIAMINE-LINKED RECEPTOR-SPECIFIC CYCLIC PEPTIDES PALATIN TECHNOLOGIES, INC. (US) 2021-08-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications MC1R, MC3R, MC5R MC4R 4/4885MC3R 2/4885MC5R 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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