SCHEMBL23752172

SCHEMBL23752172

COc1ccc(S(=O)(=O)NCC2CC2)cc1Nc1ncc(-c2cccc(-c3cccnc3)c2)o1

nearest known ligand 0.75

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDR P35968 20/20 0.75
FLT1 P17948 17/20 0.75
FLT4 P35916 17/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5474824 0.88 KDR (0.75) KDRFLT1FLT4
SCHEMBL5482886 0.86 KDR (1.00) KDRFLT1FLT4
SCHEMBL5469726 0.85 KDR (0.77) KDRFLT1FLT4
SCHEMBL5184572 0.85 KDR (0.82) KDRFLT1FLT4
SCHEMBL5184610 0.85 KDR (0.82) KDRFLT1FLT4
SCHEMBL5470358 0.83 KDR (0.72) KDRFLT1FLT4
SCHEMBL5469725 0.81 KDR (0.67) KDRFLT1FLT4
SCHEMBL5468575 0.80 KDR (0.91) KDRFLT1FLT4
SCHEMBL5464917 0.80 KDR (0.73) KDRFLT1FLT4
SCHEMBL20703577 0.80 KDR (0.90) KDRFLT1FLT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed