Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 17/20 | 0.71 |
| ▸ | DHFR | P00374 | 4/20 | 0.71 |
| ▸ | FOLR1 | P15328 | 2/20 | 0.71 |
| ▸ | SLC19A1 | P41440 | 2/20 | 0.71 |
| ▸ | SLC46A1 | Q96NT5 | 2/20 | 0.71 |
| ▸ | FOLR2 | P14207 | 1/20 | 0.71 |
| ▸ | GART | P22102 | 1/20 | 0.71 |
| ▸ | ATIC | P31939 | 1/20 | 0.71 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.71 |
| ▸ | FRK | P42685 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524781 | 0.90 | TYMS (0.74) | TYMSDHFRFOLR1SLC19A1SLC46A1 | |
| SCHEMBL12232207 | 0.85 | GART (0.83) | TYMSDHFRFOLR1SLC19A1SLC46A1 | |
| SCHEMBL12180576 | 0.85 | TYMS (0.80) | TYMSDHFRFOLR1SLC19A1SLC46A1 | |
| SCHEMBL12264580 | 0.85 | TYMS (0.69) | TYMSDHFRFOLR1SLC19A1SLC46A1 | |
| SCHEMBL23117778 | 0.85 | TYMS (0.69) | TYMSDHFRFOLR1SLC19A1SLC46A1 | |
| SCHEMBL23117779 | 0.85 | TYMS (0.69) | TYMSDHFRFOLR1SLC19A1SLC46A1 | |
| SCHEMBL24413672 | 0.85 | GART (0.85) | TYMSDHFRFOLR1SLC19A1SLC46A1 | |
| SCHEMBL13524779 | 0.84 | TYMS (0.67) | TYMSDHFRFOLR1SLC19A1SLC46A1 | |
| SCHEMBL25476851 | 0.84 | TYMS (0.64) | TYMSDHFRFOLR1SLC19A1SLC46A1 | |
| SCHEMBL22326829 | 0.84 | GART (0.87) | TYMSDHFRFOLR1SLC19A1SLC46A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |