SCHEMBL23752452

SCHEMBL23752452

N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(-c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 1.00
DPP8 Q6V1X1 12/20 1.00
DPP9 Q86TI2 12/20 1.00
DPP7 Q9UHL4 12/20 1.00
FAP Q12884 8/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23752454 1.00 DPP4 (1.00) DPP4DPP8DPP9DPP7FAP
SCHEMBL6453066 0.93 DPP4 (1.00) DPP4DPP8DPP9DPP7FAP
Hydrochloric Acid SCHEMBL7309557 0.88 DPP4 (0.91) DPP4DPP8DPP9DPP7FAP
SCHEMBL3260399 0.86 DPP4 (1.00) DPP4DPP8DPP9DPP7FAP
SCHEMBL15827032 0.86 DPP4 (1.00) DPP4DPP8DPP9DPP7FAP
SCHEMBL8231277 0.82 DPP4 (0.70) DPP4DPP8DPP9DPP7FAP
SCHEMBL7298604 0.82 DPP4 (0.80) DPP4DPP8DPP9DPP7FAP
SCHEMBL2182020 0.82 DPP4 (0.80) DPP4DPP8DPP9DPP7FAP
SCHEMBL5713150 0.82 DPP4 (0.80) DPP4DPP8DPP9DPP7FAP
SCHEMBL2195630 0.82 DPP4 (0.80) DPP4DPP8DPP9DPP7FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed