SCHEMBL2375362

SCHEMBL2375362

CC(C)COC(=O)OOC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.43
ALDH1A1 P00352 4/20 0.39
TDP1 Q9NUW8 2/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
NFKB1 P19838 1/20 0.38
PTGS1 P23219 1/20 0.38
APEX1 P27695 1/20 0.38
THPO P40225 1/20 0.38
PMP22 Q01453 1/20 0.38
KMT2A Q03164 1/20 0.38
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
P2RX4 Q99571 1/20 0.32
HPGD P15428 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL631747 0.91 TSHR (0.50) TSHRALDH1A1TDP1MEN1LMNA
SCHEMBL30018016 0.81 TSHR (0.46) TSHRALDH1A1TDP1MEN1LMNA
SCHEMBL20394089 0.80 TSHR (0.42) TSHRALDH1A1TDP1MEN1LMNA
SCHEMBL25435787 0.80 TSHR (0.54) TSHRALDH1A1TDP1MEN1LMNA
SCHEMBL37351 0.80 TSHR (0.54) TSHRALDH1A1TDP1MEN1LMNA
SCHEMBL27508290 0.79 TSHR (0.45) TSHRALDH1A1TDP1MEN1LMNA
SCHEMBL17727760 0.79 TSHR (0.45) TSHRALDH1A1TDP1MEN1LMNA
SCHEMBL6551423 0.79 TSHR (0.45) TSHRALDH1A1TDP1MEN1LMNA
SCHEMBL30216004 0.78 TSHR (0.38) TSHRALDH1A1TDP1LMNACYP3A4
Ammonia Solution, Strong SCHEMBL9998248 0.78 TSHR (0.52) TSHRALDH1A1TDP1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111234100-A Preparation method of paper reinforcing agent and application of paper reinforcing agent in papermaking 苏州派凯姆新能源科技有限公司 2020-06-05 CN claimed
US-4268651-A Two-phase vinyl chloride polymerization RHONE-POULENC INDUSTRIES (FR) 1981-05-19 US claimed
CN-118240128-A Method for preparing a composition comprising a copolymer of methyl methacrylate and methacrylic acid 盛禧奥欧洲有限责任公司 2024-06-25 CN disclosed
WO-2024019056-A1 BINDER COMPOSITION FOR LITHIUM ION BATTERY ELECTRODES ハリマ化成株式会社 2024-01-25 WO disclosed
US-11702492-B2 Methacrylic resin composition and molded article ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-07-18 US disclosed
CN-112358556-B Method for preparing chlorinated polyvinyl chloride by micro-channel reaction and product 云南正邦科技有限公司 2023-07-07 CN disclosed
US-11634572-B2 Composition comprising a copolymer comprising methyl methacrylate, (meth)acrylic acid and styrene monomers TRINSEO EUROPE GMBH (CH) 2023-04-25 US disclosed
EP-3121205-B1 ACRYLAMIDE POLYMER, PAPER STRENGTH ENHANCING AGENT, AND PAPER HARIMA CHEMICALS INC (JP) 2022-12-21 EP disclosed
EP-3647492-B1 METHOD FOR PRODUCING (METH)ACRYLAMIDE-BASED POLYMER PAPERMAKING ADDITIVE AND (METH)ACRYLAMIDE-BASED POLYMER PAPERMAKING ADDITIVE HARIMA CHEMICALS INC (JP) 2022-10-19 EP disclosed
CN-112154185-B Methacrylic resin composition and molded article 旭化成株式会社 2022-09-27 CN disclosed
US-11359043-B2 Method of preparation of a composition comprising a copolymer of methyl methacrylate and methacrylic acid TRINSEO EUROPE GMBH (CH) 2022-06-14 US disclosed
US-4785037-A HEAT RESISTANT POLYVINYL CHLORIDE BLEND MITSUBISHI RAYON COMPANY LTD. (JP) 1988-11-15 US disclosed
US-4729878-A FOR VINYL CHLORIDE POLYMERIZATION ATOCHEM (FR) 1988-03-08 US disclosed
US-4716195-A P-BENZOQUINONE TO PREVENT FORMATION OF CRUSTS SOCIETE D'EXTRUSION ET DE TRANSFORMATION (FR) 1987-12-29 US disclosed
EP-0019372-B1 RUBBER MODIFIED METHYL METHACRYLATE SYRUPS, PRODUCTION AND USE IN PRODUCING CAST SHEETS AND MOULDING MATERIALS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-07-17 EP disclosed
US-4287317-A Continuous process for producing rubber-modified methyl methacrylate syrups SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-09-01 US disclosed
US-4268651-A Two-phase vinyl chloride polymerization RHONE-POULENC INDUSTRIES (FR) 1981-05-19 US disclosed
EP-0019372-A2 Rubber modified methyl methacrylate syrups, production and use in producing cast sheets and moulding materials SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-11-26 EP disclosed
US-4070534-A SUSPENSION OR DISPERSION POLYMERIZATION THE B. F. GOODRICH COMPANY (US) 1978-01-24 US disclosed
US-4018966-A Compositions containing a reactive hydroxyl-containing vinyl chloride polymer THE B. F. GOODRICH COMPANY (US) 1977-04-19 US disclosed