⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21410495 | 0.69 | — | — | |
| SCHEMBL21373841 | 0.66 | TRPV1 (0.36) | — | |
| SCHEMBL21381411 | 0.65 | AKR1C1 (0.34) | — | |
| SCHEMBL21410336 | 0.64 | — | — | |
| SCHEMBL21373824 | 0.64 | IDO1 (0.35) | — | |
| SCHEMBL23850569 | 0.64 | FLT4 (0.34) | — | |
| SCHEMBL22576541 | 0.63 | PARG (0.31) | — | |
| SCHEMBL22758534 | 0.63 | IDO1 (0.35) | — | |
| SCHEMBL21392115 | 0.63 | — | — | |
| SCHEMBL21410338 | 0.62 | AKR1C1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4103563-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2022-12-21 | — | — | EP | disclosed |
| WO-2021160127-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2021-08-19 | — | — | WO | disclosed |