⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645705 | 1.00 | — | — | |
| SCHEMBL23754340 | 1.00 | — | — | |
| SCHEMBL10897292 | 1.00 | — | — | |
| SCHEMBL19024102 | 1.00 | — | — | |
| SCHEMBL10754606 | 0.81 | — | — | |
| SCHEMBL11565962 | 0.75 | — | — | |
| SCHEMBL130276 | 0.73 | — | — | |
| SCHEMBL5996404 | 0.72 | — | — | |
| SCHEMBL6934580 | 0.72 | — | — | |
| SCHEMBL11432606 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230135552-A1 | Compounds Useful In Inhibiting Ketohexokinase And Methods Of Making And Using The Same | INORBIT THERAPEUTICS AB (SE) | 2023-05-04 | — | — | US | disclosed |
| EP-4106762-A1 | COMPOUNDS USEFUL IN INHIBITING KETOHEXOKINASE AND METHODS OF MAKING AND USING THE SAME | INORBIT THERAPEUTICS AB (SE) | 2022-12-28 | — | — | EP | disclosed |
| CN-115315259-A | Compounds useful for inhibition of ketohexokinase and methods of making and using the same | 因奥必治疗有限公司 | 2022-11-08 | — | — | CN | disclosed |
| WO-2021161023-A1 | COMPOUNDS USEFUL IN INHIBITING KETOHEXOKINASE AND METHODS OF MAKING AND USING THE SAME | INORBIT THERAPEUTICS AB (SE) | 2021-08-19 | — | — | WO | disclosed |