SCHEMBL237545

SCHEMBL237545

O=C(Oc1ccc(-c2ccc(C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)cc1)Oc1ccc(-c2ccc(C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.49
TDP1 Q9NUW8 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KIF11 P52732 1/20 0.46
CYP2C9 P11712 2/20 0.44
KMT2A Q03164 6/20 0.44
MEN1 O00255 5/20 0.44
NPSR1 Q6W5P4 3/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
LMNA P02545 1/20 0.42
HSD17B10 Q99714 1/20 0.41
FABP7 O15540 1/20 0.41
FABP3 P05413 1/20 0.41
FABP5 Q01469 1/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
CYP1A2 P05177 1/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL236826 0.94 MAPT (0.53) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL246296 0.92 MAPT (0.51) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL235938 0.86 TDP1 (0.50) MAPTTDP1L3MBTL1KIF11KMT2A
SCHEMBL233643 0.84 KMT2A (0.55) MAPTTDP1CYP2C9KMT2AMEN1
SCHEMBL236824 0.84 KMT2A (0.55) MAPTTDP1CYP2C9KMT2AMEN1
SCHEMBL21790492 0.84 KMT2A (0.50) MAPTTDP1L3MBTL1CYP2C9KMT2A
SCHEMBL17942398 0.82 MAPT (0.53) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL23861988 0.82 MAPT (0.50) MAPTTDP1L3MBTL1KIF11CYP2C9
SCHEMBL246849 0.82 KMT2A (0.53) MAPTTDP1L3MBTL1CYP2C9KMT2A
SCHEMBL237518 0.81 MAPT (0.56) MAPTTDP1L3MBTL1KIF11KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
CN-114650915-B Layer structure with modified structure and production thereof 科思创德国股份有限公司 2024-05-31 CN disclosed
CN-117203063-A Method for locally coloring plastic parts using solid dyes in a color carrier layer 科思创德国股份有限公司 2023-12-08 CN disclosed
CN-112654508-B Improved method for locally coloring plastic parts 科思创知识产权两合公司 2022-11-08 CN disclosed
EP-4061644-A1 LAYER STRUCTURE WITH MODIFIED STRUCTURE, AND PRODUCTION THEREOF Covestro Intellectual Property GmbH & Co. KG (DE) 2022-09-28 EP disclosed
CN-114746488-A Films with special properties 科思创知识产权两合公司 2022-07-12 CN disclosed
CN-114650915-A Layer structure with modified structure and production thereof 科思创知识产权两合公司 2022-06-21 CN disclosed
CN-108778766-B Method for partially dyeing plastic parts 科思创德国股份有限公司 2021-12-31 CN disclosed
US-20210371609-A1 PLASTIC FILMS WITH REDUCED UV ACTIVITY COVESTRO LLC 2021-12-02 US disclosed
EP-3707198-B1 PLASTIC FILMS WITH REDUCED UV ACTIVITY COVESTRO DEUTSCHLAND AG (DE) 2021-10-27 EP disclosed
US-6767986-B2 A LOW MOLECULAR WEIGHT ALIPHATIC POLYCARBONATE IS PREPARED AND A SECOND STAGE WHERE THE LOW MOLECULAR WEIGHT ALIPHATIC POLYCARBONATE IS CONDENSED WITH DIARYL CARBONATE IN A MELT TRANSESTERIFICATION PROCESS BAYER AKTIENGESELLSCHAFT (DE) 2004-07-27 US disclosed
US-20040143088-A1 Method for producing polycarbonates COVESTRO DEUTSCHLAND AG (DE) 2004-07-22 US disclosed
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US disclosed
US-20040030090-A1 Polycarbonates, polyester carbonates and polyesters with special branched terminal groups BAYER AKTIENGESELLSCHAFT (DE) 2004-02-12 US disclosed
US-6646099-B2 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-11-11 US disclosed
US-20030204042-A1 Production and use of high molecular weight aliphatic polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-10-30 US disclosed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US disclosed
US-20030105272-A1 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-06-05 US disclosed
US-20020177684-A1 Process for producing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2002-11-28 US disclosed