SCHEMBL23754648

SCHEMBL23754648

CC(C)(C)OC(=O)CCOCCOCCOCCI

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 1/20 0.33
TLR2 O60603 1/20 0.32
TLR1 Q15399 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21634207 1.00 STING1 (0.33) STING1TLR2TLR1HDAC3HDAC1
SCHEMBL20579347 1.00 STING1 (0.33) STING1TLR2TLR1HDAC3HDAC1
SCHEMBL29602543 1.00 STING1 (0.33) STING1TLR2TLR1HDAC3HDAC1
SCHEMBL21634210 0.98 STING1 (0.34) STING1TLR2TLR1HDAC3HDAC1
SCHEMBL18843243 0.90 STING1 (0.37) STING1TLR2TLR1HDAC3HDAC1
SCHEMBL5735427 0.90 STING1 (0.37) STING1TLR2TLR1HDAC3HDAC1
SCHEMBL1536707 0.90 STING1 (0.37) STING1TLR2TLR1HDAC3HDAC1
SCHEMBL5737163 0.90 STING1 (0.37) STING1TLR2TLR1HDAC3HDAC1
SCHEMBL29155906 0.90 STING1 (0.37) STING1TLR2TLR1HDAC3HDAC1
SCHEMBL25933065 0.90 STING1 (0.37) STING1TLR2TLR1HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021162493-A1 PROTEIN KINASE DEGRADATION INDUCING COMPOUND, AND USE THEREOF 보로노이 주식회사 2021-08-19 WO disclosed