Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | ASPH | Q12797 | 3/20 | 0.57 |
| ▸ | KDM8 | Q8N371 | 3/20 | 0.57 |
| ▸ | KDM5A | P29375 | 2/20 | 0.57 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.57 |
| ▸ | KDM6B | O15054 | 1/20 | 0.57 |
| ▸ | TET3 | O43151 | 1/20 | 0.57 |
| ▸ | KDM4A | O75164 | 1/20 | 0.57 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KDM5C | P41229 | 1/20 | 0.57 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.57 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.57 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.57 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.57 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.57 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.57 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.57 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12258250 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL31032261 | 0.83 | KDM4E (0.52) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL29272073 | 0.83 | KDM4E (0.52) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL101547 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL25687802 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL30237069 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL29272351 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL20052125 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL29272328 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL11535592 | 0.79 | KDM4E (0.52) | KDM4EALDH1A1ASPHKDM8KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021163464-A1 | TREATMENT AND PREVENTION OF CAPILLARY MALFORMATION-ARTERIOVENOUS MALFORMATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-08-19 | — | — | WO | disclosed |