Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.85 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.85 |
| ▸ | POLB | P06746 | 2/20 | 0.83 |
| ▸ | STAT3 | P40763 | 1/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.83 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | NT5E | P21589 | 1/20 | 0.71 |
| ▸ | JAK2 | O60674 | 1/20 | 0.70 |
| ▸ | TYK2 | P29597 | 1/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23096186 | 1.00 | KDM4E (0.85) | KDM4EL3MBTL1POLBSTAT3SMN1; SMN2 | |
| SCHEMBL19241698 | 0.98 | KDM4E (0.88) | KDM4EL3MBTL1POLBSTAT3SMN1; SMN2 | |
| SCHEMBL30828578 | 0.96 | GAA (0.78) | KDM4EL3MBTL1POLBSTAT3SMN1; SMN2 | |
| SCHEMBL30828573 | 0.96 | GAA (0.78) | KDM4EL3MBTL1POLBSTAT3SMN1; SMN2 | |
| SCHEMBL23734986 | 0.92 | GAA (0.85) | KDM4EL3MBTL1POLBSTAT3SMN1; SMN2 | |
| SCHEMBL14716526 | 0.92 | KDM4E (1.00) | KDM4EL3MBTL1POLBSTAT3SMN1; SMN2 | |
| SCHEMBL29013035 | 0.91 | POLB (1.00) | KDM4EL3MBTL1POLBSTAT3SMN1; SMN2 | |
| SCHEMBL30828563 | 0.91 | POLB (0.77) | KDM4EL3MBTL1POLBSTAT3SMN1; SMN2 | |
| SCHEMBL19241697 | 0.90 | GAA (0.88) | KDM4EL3MBTL1POLBSTAT3SMN1; SMN2 | |
| SCHEMBL20284421 | 0.90 | PTPN1 (0.77) | KDM4EL3MBTL1POLBSTAT3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3411140-B1 | METHOD FOR SEPARATING ACETYLENE FROM A GAS MIXTURE | UNIV LIMERICK (IE) | 2021-08-18 | — | — | EP | disclosed |