Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | POLD1 | P28340 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 12/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.35 |
| ▸ | POLG | P54098 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23760855 | 1.00 | POLB (0.38) | POLBPOLA1POLD1P2RY2P2RX3 | |
| SCHEMBL19187105 | 1.00 | POLB (0.38) | POLBPOLA1POLD1P2RY2P2RX3 | |
| SCHEMBL23760859 | 1.00 | POLB (0.38) | POLBPOLA1POLD1P2RY2P2RX3 | |
| SCHEMBL20058731 | 1.00 | POLB (0.38) | POLBPOLA1POLD1P2RY2P2RX3 | |
| SCHEMBL24081814 | 0.97 | BTN3A1 (0.37) | POLBPOLA1POLD1P2RY2P2RX3 | |
| SCHEMBL19777920 | 0.97 | BTN3A1 (0.37) | POLBPOLA1POLD1P2RY2P2RX3 | |
| SCHEMBL23760746 | 0.97 | BTN3A1 (0.37) | POLBPOLA1POLD1P2RY2P2RX3 | |
| SCHEMBL24162670 | 0.90 | P2RY2 (0.37) | POLBPOLA1POLD1P2RY2P2RY4 | |
| SCHEMBL23171644 | 0.87 | P2RY1 (0.32) | POLBPOLA1POLD1 | |
| SCHEMBL24081891 | 0.86 | POLA1 (0.37) | POLBPOLA1POLD1P2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865136-A1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR CORONA VIRUS TREATMENT | ATEA Pharmaceuticals, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |