Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960502 | 0.81 | SLC6A2 (0.47) | TSHRCYP1A2KCNA5KCNH2CYP2C19 | |
| SCHEMBL12725114 | 0.81 | SLC6A2 (0.47) | TSHRCYP1A2KCNA5KCNH2CYP2C19 | |
| SCHEMBL5960481 | 0.81 | SLC6A2 (0.47) | TSHRCYP1A2KCNA5KCNH2CYP2C19 | |
| SCHEMBL21132105 | 0.70 | SLC6A2 (0.42) | TSHRCYP1A2KCNA5KCNH2CYP2C19 | |
| SCHEMBL22298872 | 0.69 | HTT (0.43) | TSHRCYP1A2CYP2C19ALDH1A1CYP2D6 | |
| SCHEMBL17015047 | 0.69 | HTT (0.43) | TSHRCYP1A2CYP2C19ALDH1A1CYP2D6 | |
| SCHEMBL22298875 | 0.69 | HTT (0.43) | TSHRCYP1A2CYP2C19ALDH1A1CYP2D6 | |
| SCHEMBL21291442 | 0.69 | KCNA5 (0.38) | TSHRCYP1A2CASRKCNA5KCNH2 | |
| SCHEMBL24827566 | 0.68 | KCNA5 (0.46) | TSHRCYP1A2KCNA5KCNH2CYP2C19 | |
| SCHEMBL19002476 | 0.68 | KCNA5 (0.46) | CXCR4TSHRCYP1A2KCNA5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253614-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CD73 | PELOTON THERAPEUTICS, INC. (US) | 2021-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253614-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CD73 | ENTPD5, NT5E, ENTPD1 | CXCR4 667/4885TSHR 2778/4885CYP1A2 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.