Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 11/20 | 0.54 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23270490 | 0.92 | NT5E (0.57) | NT5EP2RY6P2RY14 | |
| SCHEMBL31078154 | 0.92 | NT5E (0.57) | NT5EP2RY6P2RY14 | |
| SCHEMBL31622323 | 0.92 | NT5E (0.57) | NT5EP2RY6P2RY14 | |
| SCHEMBL23765441 | 0.90 | NT5E (0.55) | NT5EP2RY6P2RY14 | |
| SCHEMBL23765457 | 0.89 | NT5E (0.53) | NT5E | |
| SCHEMBL23765296 | 0.87 | NT5E (0.57) | NT5EP2RY6P2RY14 | |
| SCHEMBL23765505 | 0.85 | NT5E (0.55) | NT5EP2RY6P2RY14 | |
| SCHEMBL23765282 | 0.85 | NT5E (0.59) | NT5E | |
| SCHEMBL23765346 | 0.84 | NT5E (0.51) | NT5EP2RY6P2RY14 | |
| SCHEMBL23765559 | 0.83 | NT5E (0.52) | NT5EP2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253614-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CD73 | PELOTON THERAPEUTICS, INC. (US) | 2021-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253614-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CD73 | ENTPD5, NT5E, ENTPD1 | NT5E 2/4885P2RY6 63/4885P2RY14 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.