Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2152971 | 0.86 | CYP1A2 (0.40) | CYP1A2CA12CA1CA2CA9 | |
| SCHEMBL1280731 | 0.85 | CA12 (0.34) | CYP1A2CA12CA1CA2CA9 | |
| SCHEMBL19451246 | 0.84 | CA14 (0.41) | CA14 | |
| SCHEMBL31618131 | 0.84 | CA14 (0.41) | CA14 | |
| SCHEMBL23765763 | 0.83 | BLM (0.42) | CA1CA2CA14 | |
| SCHEMBL24046494 | 0.83 | CA14 (0.35) | CA14 | |
| SCHEMBL21107882 | 0.83 | CA14 (0.35) | CA14 | |
| SCHEMBL3486020 | 0.83 | CA14 (0.42) | CA14 | |
| SCHEMBL23765974 | 0.82 | CA14 (0.38) | CA12CA1CA14 | |
| SCHEMBL31022630 | 0.82 | CA12 (0.36) | CYP1A2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865152-A1 | TARGETED PROTEASE DEGRADATION PLATFORM | Eubulus Biotherapeutics Inc. (CN) | 2021-08-18 | — | — | EP | disclosed |