Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 2/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25756187 | 0.95 | CA14 (0.43) | CA14HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL24068670 | 0.88 | CA14 (0.39) | CA14HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL24068636 | 0.88 | CA14 (0.39) | CA14HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL24068347 | 0.88 | CA14 (0.39) | CA14HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL24068638 | 0.87 | CA14 (0.42) | CA14HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL23765714 | 0.87 | CA14 (0.42) | CA14HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL23765705 | 0.87 | CA14 (0.42) | CA14HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL18499075 | 0.87 | CA14 (0.54) | CA14HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL3265219 | 0.87 | CA14 (0.54) | CA14HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL24068663 | 0.86 | CA14 (0.40) | CA14HDAC1HDAC2HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865152-A1 | TARGETED PROTEASE DEGRADATION PLATFORM | Eubulus Biotherapeutics Inc. (CN) | 2021-08-18 | — | — | EP | disclosed |