SCHEMBL23766132

SCHEMBL23766132

CNCCOCCOCCOCCC(=O)Nc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.56
▸ CRBN Q96SW2 14/20 0.53
▸ BRD4 O60885 3/20 0.53
▸ MAP1LC3B Q9GZQ8 5/20 0.51
▸ TNF P01375 1/20 0.50
▸ IL1B P01584 1/20 0.50
▸ IKZF1 Q13422 1/20 0.50
▸ DDB1 Q16531 1/20 0.50
▸ IKZF3 Q9UKT9 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25031652 1.00 STAT3 (0.56) STAT3CRBNBRD4MAP1LC3BTNF
SCHEMBL23765963 0.93 STAT3 (0.56) STAT3CRBNBRD4MAP1LC3BTNF
SCHEMBL23766258 0.93 STAT3 (0.56) STAT3CRBNBRD4MAP1LC3BTNF
SCHEMBL22252682 0.92 CRBN (0.55) STAT3CRBNBRD4MAP1LC3BTNF
SCHEMBL19438857 0.90 CRBN (0.55) STAT3CRBNBRD4MAP1LC3BTNF
SCHEMBL20913661 0.90 CRBN (0.55) STAT3CRBNBRD4MAP1LC3BTNF
SCHEMBL19438825 0.90 CRBN (0.55) STAT3CRBNBRD4MAP1LC3BTNF
SCHEMBL30577345 0.90 CRBN (0.55) STAT3CRBNBRD4MAP1LC3BTNF
SCHEMBL21855255 0.90 CRBN (0.57) STAT3CRBNBRD4MAP1LC3BTNF
SCHEMBL29836960 0.90 CRBN (0.57) STAT3CRBNBRD4MAP1LC3BTNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3865152-A1 TARGETED PROTEASE DEGRADATION PLATFORM Eubulus Biotherapeutics Inc. (CN) 2021-08-18 — — EP disclosed
Send feedback